Association between Glycemic Control Parameters in Sudanese Diabetic Patients

Author(s):

Alneil Abdalla Hamza* and Elfaki EM

Introduction: Glycated Hemoglobin HbA1c and Fasting Blood Glucose FBG measurements provide useful information about glycemic control status in diabetic patients. Estimated Average blood Glucose eAG is often calculated to translate HbA1c result into terms that closely represent a daily reading of Fasting Blood Glucose FBG. Objective: This study was carried out to evaluate the glycemic control status and the association between FBG and eAG in diabetic patients. Methods: This retrospective cohort study was conducted on FBG, HbA1c tests results of 687 diabetic patients 324 males and 363 females who were attending the diabetic care center in Khartoum state. HbA1c level greater than 7 percent represents the cutoff for poor glycemic control as well, fasting blood glucose levels of less than 130 mgbydl, 130 to 180 mg by dl, and greater than 180 mg by dl were used to categorize the patients into three subgroups of glycemic status A, B and C respectively. eAG was calculated by using the regression equation: eAG mg by dL=28.7 multiply HbA1c NGSP, percent to 46.7. Results: The rate of poor glycemic control was found to be 76.9 percent, 80.6 percent for males, and 73.6 percent for females. A positive significant correlation was observed between FBG and eAG within the study groups p less than 0.001 while for the subgroups the association was found significantly different only in the more poor glycemic control group C p equal to 0.369, p less than 0.001. Conclusion: Calculation of estimated average blood glucose with fasting blood glucose help patients and clinicians in assessment of glycemic control status.