Design of an Effective Nutraceutical (HR15) for Physical Performance and Endurance

Author(s):

Javier Moran*

The global dietary supplements market has expanded, offering products for athletes that promise enhanced well-being and sports performance. However, standard definitions and regulatory frameworks are lacking, highlighting the need for high-quality scientific research. Rigorous methods are essential to differentiate strong findings from weaker studies. Key considerations in designing quality studies for athlete supplements include power calculations, characterization of supplement components, participant selection, outcome measure justification, error assessment, and blinding techniques. Natural ingredients showing promise in sports performance include Rhodiola rosea, which reduces stress and fatigue, and Rhaponticum carthamoides, which enhances strength and muscle recovery. Fatty acids like conjugated linoleic acid and medium-chain triglycerides benefit muscle damage reduction, endurance, and body mass regulation. HR15, a novel supplement, was developed with strategies to enhance bioavailability using lipid-based vehicles, addressing solubility, stability, and permeability challenges. Preclinical studies in Caenorhabditis elegans indicated increased lifespan, antioxidant effects, and metabolic pathway alterations. Clinical trials showed that HR15 ingredients improved antioxidant defenses, reduced oxidative damage, enhanced emotional well-being, and mitigated oxidative stress, inflammation, muscle damage, and fatigue in active individuals. These findings support HR15's potential to improve sports performance and well-being, advocating for safer and more effective supplements for athletes.