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In Vitro Evaluation Performance of Recently Developed Rapid Diagnostic Test for Detecting Carbapenemases: The Multiplex Lateral Flow Assay

Author(s):

Bansidhar Tarai*, Sonu kumari Agrawal

Carbapenem Resistant Enterobacteriaceae (CRE) and Carbapenemase- Producing Organisms (CPOs) pose a serious threat to public health. Due to their vast range of antibiotic resistance, which excludes carbapenems and affects the majority of antimicrobial agent classes, leaving relatively few alternatives to treat people who are infected. In this study, we compared the performance of the RESIST-5 O.K.N.V.I. and RESIST ACINETO test to Vitek-2 in detecting the carbapenemases among a large number of clinical isolates in India. Performance of ICT Assay in Comparison to Vitek, The IC test indings revealed 94.44% concordance and 2% discordant with the Vitek results with 94.44% sensitivity and 100 %speci icity. The RESIST-5 O.K.N.V.I. and RESIST ACINETO assay is quite effective at detecting carbapenemase genes. These assays are also a quick, simple, and effective technique for use in clinical microbiology laboratories.


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Annals of Medical and Health Sciences Research The Annals of Medical and Health Sciences Research is a monthly multidisciplinary medical journal.
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