Histopathological Review of Nephrectomy Specimens in Ile-Ife: A 10-Year Retrospective Review

Author(s):

Adefidipe Adeyemi Abiola*, Adefehinti Olugbenga, Komolafe Akinwumi Oluwole, Alade Oluwatosin T, Ogunrinde Opeoluwa Victor, Olorunsola Ifeoluwa S and Adelusola Kayode A

Aim and objectives: The study aims to determine the common histopathological findings in the nephrectomy specimens received at the O.A.U.T.H.C. Ile-Ife over 10 years period.

Method: This is a cross-sectional retrospective histopathologic review of nephrectomy specimens received at the department of morbid anatomy and forensic medicine, O.A.U.T.H.C Ile- Ife from May 2012 to May 2020.

Results: There were 72 nephrectomy specimens seen in our histopathology department over the period of the study, 41 (56.9%) were females and 31 (43.1%) were males with an F:M ratio of 1.3:1. Seventy-six percent of the cases were malignant while 23.6% were benign. Renal cell carcinoma was the commonest indication for performing nephrectomy in the study period accounting for 28 cases (38.9%) followed by Wilms tumor which constitutes 24 of the cases (33.3%) out of the total. Cystic diseases of the kidney accounted for most (70.6%) benign conditions seen in this study followed by angiomyolipoma (11.8%). Fifty percent of the nephrectomies were done on the left kidney while 48.6% were done on the right kidney and 1.4% were bilateral.

Conclusion: Neoplastic lesions were commoner than non-neoplastic lesions in the nephrectomy specimens received during the study period. Renal cell carcinoma was the most common neoplasm seen and cystic diseases of the kidney were the most common non-neoplastic lesion observed.