Investigation the Development of Metabolic Syndrome for Type 2 Female Diabetic through Serpin E1, Chemoattractant Protein-1 and Adiponectin

Author(s):

Lamia AM AL-Mashhedy*

In this study, 54 female patients with type 2 diabetes and 36 non-diabetics took part, with obese and non-obesity persons compared to an apparently healthy control group. The serpin E1 and monocyte chemoattractant protein-1 were measured by ELISA sandwich while the colorimetric methods were used for calculating HbA1C, serpin E1 (serine proteinase inhibitors) and lipid peroxidation. The levels of serpin E1 (PAI-1) and monocyte chemo attractant protein -1 in the blood of non-obese women differed signi icantly from those of obese individuals (p=0, 05). Similarly, there was a signi icant difference between the receptor levels of no obese female patients and serum controls from obese females (p=0.05). The values of serpin E1, monocyte chemoattractant protein -1, HbA1C were increased in patients with type 2 diabetes who have the highest TG, TC, vLDL, LDL and also decreased for HDL and adiponectin in obese females. In this study, parameter was compared with adiponectin under review.