Objective: To determine the relationship between the Ankle-Brachial Index ABI and glycemic control in patients with type 2 diabetes mellitus. Materials & Methods: This descriptive, cross-sectional, correlational study was completed with 175 patients presenting to the internal diseases clinic of an education and research hospital between April and May 2021, consenting to take part, and meeting the inclusion criteria. Age, gender, Body Mass Index (BMI), antidiabetic therapy used, statin and acetylsalicylic acid use, and biochemistry parameters were evaluated. p values<0.05 were regarded as significant. Results: The mean age of the patients in this research was 57.91 years ± 9.10 years (min: 23, max: 79), 58.9% were women, and 73.1 had normal ABI scores (0.9-1.4). Significant associations were observed between gender, retinopathy or hypertension and ABI scores. Cholesterol, Low-Density Lipoprotein (LDL), and systolic and diastolic blood pressures were also significantly higher in the group with normal ABI scores (0.9-1.4). Significant weak, negative correlation was determined between patient ABI values and total cholesterol, LDL, and albuminuria values. Conclusion: ABI values in the present study were higher among women and patients with retinopathy and hypertension, while no association was observed with glycemic control. Cholesterol, LDL, and systolic and diastolic blood pressure values increased in individuals with normal ABI scores, and total cholesterol, LDL, and albuminuria decreased as ABI increased
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