Unilateral Closed Lip Schizencephaly with Septo‑Optic Dysplasia

Author(s):

Bhatnagar S, Kuber R, Shah D, Kulkarni VM

Schizencephaly is a rare malformation of the central nervous system. Both genetic and non�genetic etiologies like prenatal infections or ischemia have been postulated. Clinical manifestations most often include varying degrees of developmental delay, motor impairment and seizures. It can be associated with septo�optic dysplasia (SOD), optic nerve hypoplasia and absence of septum pellucidum, pachygyria, polymicrogyria, heterotopia and arachnoid cysts. We report a case of unilateral closed lip schizencephaly with SOD.