Early Diagnosis of an Aggressive Childhood Malignancy with Flow-cytometric Immunophenotyping: A Case Report
Citation: Kishore M, et al. Early Diagnosis of an Aggressive Childhood Malignancy with Flowcytometric Immunophenotyping: A Case Report. Ann Med Health Sci Res. 2019;9:490-493
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Abstract
Serous effusions may occur as complications in different types of lymphomas. Among these, pleural effusions are commonly observed; however, involvement of peritoneal or pericardial cavity is rare. Different diagnostic modalities like cytological examination, immunocytochemistry, cytogenetics have been used to diagnose various malignancy, thereby attaining a fast and accurate diagnosis. As effusion in lymphoma is associated with poor outcome, an early diagnosis is very much important. We describe a case of aggressive Non-Hodgkin lymphoma, i.e., Burkitt lymphoma in a previously healthy 7-year-old male child, where the diagnostic ascitic & pleural fluid cytomorphology in conjunction with flow-cytometric immuno-phenotypic analysis of the effusion helped in clinching an early diagnosis.