Research Article
Accelerated Brain Age in Young to Early Middle-Aged Adults after Mild to Moderate COVID-19 Infection
Author(s):
Shelli R Kesler*, Oscar Y. Franco-Rocha, Alexa De La Torre Schutz, Kimberly A. Lewis, Rija M Aziz, W. Michael Brode and Esther Melamed
Background: Cognitive decline is a common adverse effect of the Coronavirus Disease of
2019 (COVID-19), particularly in the post-acute disease phase. The mechanisms of cognitive
impairment after COVID-19 (COGVID) remain unclear, but neuroimaging studies provide
evidence of brain changes, many that are associated with aging.
Aim of the study: To calculate Brain Age Gap (BAG), which is the difference between brain age
and chronological age.
Material and Methods: BAG was measured in a cohort of 25 mild to moderate COVID-19
survivors (did not experience breathlessness, pneumonia, or respiratory/organ failure) and 24
non-infected controls (mean age=30 ± 8) using Magnetic Resonance Imaging (MRI).
Results: BAG was significantly higher in the COVID-19 group (F=4.22, p=0.046).. Read More»
Select your language of interest to view the total content in your interested language
Annals of Medical and Health Sciences Research received 24805 citations as per google scholar report