Alka Hande

Department of Oral Pathology and Microbiology, Sharad Pawar Dental College, Datta Meghe Institute of Medical Sciences (Deemed to be University), Sawangi (Meghe), Wardha, Maharashtra, India

Publications

• Reviews   
  Correlation of Clinicopathological Features With Prognosis in Oral Squamous Cell Carcinoma with and Without Oral Submucous Fibrosis
  Author(s): Alka Hande*, Archana Sonone, Madhuri Gawande and Swati Patil
  
  Background: Oral Squamous Cell Carcinoma in the background of Oral Sub Mucous Fibrosis (OSCC with OSMF) is one of the most common malignancies in South and South-East Asian countries. The clinical presentation of OSCC is variable, and is related with the site , progression time, association with precancerous lesions and risk factors. Recently, it has been proposed that OSCC with OSMF constitutes a clinicopathologically distinct disease, the differences of which believed to arise from differential mechanisms of areca nut carcinogenesis. The proposed unique nature of OSCC in this altered condition relates to younger age of presentation, better histological grade of differentiation of the tumor, and lesser potential for nodal metastasis. According to the existing knowledge, the prognostic indicators of OSCC with OSMF in context to the cli.. Read More»