Reviews
Efficacy of Immunomodulatory Biologic Treatments in Atopic Dermatitis Patients: Systematic Review and Meta-analysis
Author(s):
Nasser Bader Alrumaidhi, Nasser Bader Alrumaidhi*, Bashair Abdullelah Hussin, Sarah Waleed Alnafe and Dania Ali Alhindawi
Background: Skin lesional from Atopic Dermatitis (AD) patients characterized by. elevated expression of the T2 cytokine axis takes place in ad, in which interleukin (IL)-4 and IL-13 play a major role. Aim: This work aims to determine the efficacy of immunomodulatory biologic treatments in atopic dermatitis patients. Materials and Methods: A systematic search was performed over different medical databases to identify Dermatology studies, which studied the outcome of the Biologic group versus the Placebo group of atopic dermatitis patients. Using the meta-analysis process, either with fixed or random-effects models, we conducted a meta-analysis on one of the following scores: eczema area and severity index (EASI), dermatology life quality index (DLQI) score and patient-oriented eczema measure (POEM) score a.. Read More»
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