Research Article
Specific and Acute Toxicity Estimate of New Domestic Nootropic Preparation
Author(s):
Kasimov Eldor*, Inoyatova Feruza, Azimova Sevara, Saydalikhodjaeva Ozoda, Boboeva Zukhra and Nasillayev Feruz
Purpose of the Research: To comparative specific properties and acute toxicity researching of a new domestic no otropic Nootrotem preparation. Materials and Methods: The research object was Nootrotem preparation, it is solution for infusion produced by LLC Temur Med Farm Uzbekistan and comparison preparations Mexidol and Piracetam. The preparation anti hypoxic activity was studied under model of normobaric hypoxic hypoxia in experiments on 18 white male mice, divided into 3 groups. They are Group 1 control to 0.9 percent, 0.3 ml volume NaCl solution were injected intravenously during 3 days, Group 2 experimental within 3 days no otrotem was injected at the dose of 337.5 mg by kg 0.3 ml, Group 3 comparison for 3 days, diluted comparison preparations Mexidol and Piracetam were injected intravenously at a dose of 337.5 mg by kg 0.3 ml. Acute toxicity was.. Read More»
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