Original Article
Potential Biomarker for Peri-Implantitis: A Cross-Sectional Study of Type I Collagen Levels in the Sulcular Fluid in relation to Cross-Linked N-Telopeptide and Calprotectin
Author(s):
Dalal Hazam Alotaibi, Mansour KA Assery*, Maha S Mezied and Abdulla AlAzhari
Background: Peri-implantitis results after inflammation and bone resorption around implant site. The crevicular fluids present in that region are rich in N-Telopeptide (NTx) and Calprotectin, which are assumed as potential biomarkers. The aim was to assess and compare the calprotectin and NTx levels in the peri-implant sulcular fluid (PISF) from implant sites with or without peri-implantitis. Methodology: A total of fifty healthy patients with a single dental implant were recruited. The peri-implant clinical parameters, namely; probing pocket depth (PPD), bleeding upon probing (BOP), and gingival index (GI), was recorded for each patient. Radiographic images for each implant were obtained to assess the bone loss. PISF was collected using sterile paper strips for detection of calprotectin and NTx levels using the ELISA tech.. Read More»
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