Reviews
Anticancer Effect of AntiMalarial Artemisinin Compounds
Author(s):
Das AK*
The antiâÃ?Â?Ã?Â?malarial drug artemisinin has shown anticancer activity in vitro and animal experiments, but experience in human cancer is scarce. However, the ability of artemisinins to kill cancer cells through a variety of molecular mechanisms has been explored. A PubMed search of about 127 papers on antiâÃ?Â?Ã?Â?cancer effects of antimalarials has revealed that this class of drug, including other antimalarials, have several biological characteristics that include anticancer properties. Experimental evidences suggest that artemisinin compounds may be a therapeutic alternative in highly aggressive cancers with rapid dissemination, without developing drug resistance. They also exhibit synergism with other anticancer drugs with no increased toxicity toward normal cells. It has been found that semisynthetic artemisinin derivatives have much higher antitumor activity than t.. Read More»
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The Annals of Medical and Health Sciences Research is a bi-monthly multidisciplinary medical journal.