Research Article
Biochemical Markers of Oxidative Stress in Patients with Inflammatory Bowel Diseases
Author(s):
Grazyna Mierzwa, Maria Klopocka, Daria Kupczyk and Beata Augustynska*
Background: Inflammatory Bowel Diseases (IBD) is a group of diseases of
unexplained etiology, characterized by periods of remissions and
exacerbations. Reactive Oxygen Species (ROS) as far as disorders of
balance between levels of prooxidants and antioxidants may also
participate in upraise of IBD. The aim of our study was an assessment of
the antioxidative barrier of the organism in patients with inflammatory
bowel disease.
Material and methods: The study group consisted of 99
patients (80 with IBD as a study group and 19 healthy as a control group) of
Jan Biziel University Hospital in Bydgoszcz, Poland. Venous blood was a
material for biochemical analysis: HT, GSH, GPXp, GPXRBC, GST, GR,
SOD-1, MDA, NO2-/NO3- and CP. Results: There were statistically
significant differences in oxidative .. Read More»
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