Irina Nita

Department of Oncology, Elias Hospital, Bucharest, Romania

Publications

• Research Article   
  Analysis of Oxidative Stress in Patients with Breast Cancer and Obesity
  Author(s): Irina Nita, Dumitru Cristinel Badiu, Dumitru Cristinel Badiu, Rodica Maricela Anghel, Rodica Maricela Anghel, Maria Iuliana Gruia, Andra Maria Stancu, Loredana Sabina Cornelia Manolescu, Irina Nita, Iuliana Pantelimon, Dragos Eugen Georgescu, Dragos Eugen Georgescu, Georgia Luiza Serbanescu, Georgia Luiza Serbanescu, Anca Zgura*, Anca Zgura, Laurentia Nicoleta Gales and Laurentia Nicoleta Gales
  
  Background: Breast cancer is a major source of public health concern. Our work aims to study the role of oxidative stress in breast pathophysiology. Materials & Methods: A group of 39 patients diagnosed and treated for breast cancer was followed in a prospective, observational, nonrandomized study to assess the serum oxidative stress levels. Thus, the following parameters were determined: Malondialdehyde (MDA) concentration as a measure of lipid peroxidation reaction, serum thiol concentration as end products of oxidative degradation of proteins, and total level of antioxidants. Results: 81.9% of these patients have an excess of adipose tissue (overweight or obesity). A positive correlation was obtained between the serum peroxides values and obesity as measured by Body Mass Index (BMI) (p<0.01) and waist circumference (p<0.0.. Read More»
  10.54608.annalsmedical.2021.9