Iyeopu Miniakiri Siminialayi

Department of Pharmacology, College of Health Sciences, University of Port Harcourt, Choba, Rivers State, Nigeria

Publications

• Research Article   
  Nasal Decongestant Effects of Vitellaria paradoxa (Shea Butter) Extracts, a Hospital Based Study
  Author(s): Opubo Benedict Lilly-Tariah, Iyeopu Miniakiri Siminialayi, Sokiprim Akoko*, Ediriverere Nosa Oghenekaro and Musa Stephen
  
  Background: Mucosal inflammation underlies many of the specific and interrelated factors that contribute to nasal congestion and shea butter is used by local healers as a treatment for inflammatory conditions including nasal congestion. The aim of this study was to evaluate the effects of extracts of Shea butter on diagnosed patients with Nasal congestion. Methods: Forty-Two study participants were randomized into two main groups-control (standard of care-Cetirizine, Xylometazoline) and then the shea butter/shea butter extract group which was further subdivided into 4 groups-extract 1 (saponifiable); extract 2 (nonsaponifiable), extract 3 (Steroid) and shea butter. Following the administration of the various drugs, participants were followed for 24 hours with nasal washout samples taken at baseline and 24 hours later, t.. Read More»