Reviews
Sialochemistry and Dental Caries in Down’s syndrome: A Gel Electrophoresis
Author(s):
Punithavathy R*, Narendra Kumar R and Kamalsha SK
Background: Scientific clue of awareness, perceptivity to dental caries in the population with Down’s syndrome is hampered and adverse, making it challenging to establish firm conclusions. Wide range of developmental delays and physical disabilities caused by a genetic disease, Down’s syndrome, which is caused when abnormal cell division results in extra genetic material from chromosome 21. This disease has an incidence of 1 in 600-700 live births. One of the most prominent oral manifestations of Down’s syndrome is low incidence of dental caries. Diminished salivary pH and bicarbonate levels. Biochemical alterations in saliva, delayed eruption, less susceptibility to cariogenic environment, shallow fissures of teeth, all contribute to the lower risk of dental caries. Aim: To compare the glycoproteins, pro.. Read More»
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