Original Article
A Survey on Selective Immunoglobulin A Deficiency Among Asthmatic Adults with Variable Total Immunoglobulin E levels in Tehran: An Office-Base Study
Author(s):
Khosrow Agin*
Background: Selective IgA deficiency (SIgAD) is one of the most common primary antibody immunodeficiency diseases. The prevalence in Asia is lower than other areas. Asthma and allergic diseases are common among the SIgAD population. The aim of this study was to evaluate the prevalence of SIgAD among the adult asthmatic patients with variable immunoglobulin E (IgE) levels in serum. Patients and methods: 507 asthmatic patients of various age and sex who sequentially enrolled in the outpatient respiratory clinic were selected. Asthma diagnosis was based on the pulmonologist’s diagnostic and ATS criteria. IgA and total IgE levels in serum were measured according to manufacturer’s recommended kits. Results: 64 (13%) subjects detected as SIgAD. Mean age recorded 34.5 ± 13.9 SD years. The patie.. Read More»
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The Annals of Medical and Health Sciences Research is a monthly multidisciplinary medical journal.