Research Article
Effectiveness of Antioxidants in Oral Submucous Fibrosis: A Retrospective Study
Author(s):
Manivasagam D, Muthukrishnan A* and Chaudary Manjari
Background: Oral Submucous Fibrosis (OSMF) is defined as an insidious chronic disease affecting any part of the oral cavity and sometimes pharynx. Although, occasionally preceded by and/or associated with vesicle formation, it is always associated with juxta epithelial inflammatory reaction followed by fibroelastic changes in lamina propria with epithelial atrophy leading to stiffness of oral mucosa causing trismus and difficulty in eating. It is a condition with increased oxidative stress leading to free radical release. Thus, the aim of the study is to assess the therapeutic effectiveness of antioxidants in oral submucous fibrosis.
Materials & Methods: Retrospective analyses of 52 clinically diagnosed OSMF patients were included in the study. The habit history was recorded. The patients were administered systemic antioxidants after habit.. Read More»
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