Mir Younis Ali

Department of Neurosurgery, Shere-i-Kashmir institute of Medical Sciences, Kashmir, India

Publications

• Research Article   
  Lumbosacral Chordomas: The Enigmatic and Dreaded Entity
  Author(s): Mir Younis Ali, Mohsin Fayaz* and Abdul Rashid Bhat
  
  Introduction: Primary tumours of the spine are rare, accounting for less than 5% of all osseous neoplasms and less than 0.2% of all cancers. Among all primary tumours of the spine, the incidence of primary malignant tumours varies between 32% and 71%. The most common primary malignant tumours of the spine are chordoma and sacral sarcomas like chondrosarcoma, osteosarcoma and Ewing sarcoma. Chordoma is a slow-growing, locally aggressive neoplasm of bone which arises from embryonic remnants of the notochord, with an overall incidence of 0.08 per 100,000 individuals accounting for 40% of all primary sacral tumours. The tumour has a delicate pseudo capsule, in which satellite lesions and occult extension are frequent. Hence, local recurrence is expected due to failure to achieve negative surgical margins. Chordomas are insensitive to chemotherap.. Read More»