Nuha A Alkhattabi

Department of Biochemistry, King Abdulaziz University, Jeddah, Saudi Arabia

Publications

• Research Article   
  Comparing between Hydroxyurea and Non-Hydroxyurea Anti-inflammatory Cytokines in Sickle Cell Anemia Saudi Patients
  Author(s): Nesrin I Tarbiah*, Nuha A Alkhattabi, Maryam M Alhemadi, Huda S Almutairi, Reem Y Alzahri, Hend Hussain and Reema S Alamri
  
  Sickle Cell Anemia SCA is a hemolytic deficiency that is typified by strangely formed sickles red blood cells that are expelled from circulation at expanded rates, leading to anemia. It is caused by inheritance of hemoglobin Hb that has mutated, which compared to adult normal Hb, contains a single amino acid substitution, where at the sixth residue valine substitutes glutamic acid in the Hb tetramer in both of the two B chains. For SCA patients, chronic inflammatory conditions are linked to high levels of inflammation markers, including cytokines and adhesion molecules. Cytokines are a group of small proteins that are essential in cell signaling. The immuno regulatory molecules known as anti-inflammatory cytokines control the response of pro inflammatory and have gained attention recently as anti-inflammatory mediator in SCA patients. The most interesting anti-inflammatory cytokines a.. Read More»