Research Article
Efficiency of Cichorium Intybus in Reducing
Hepatotoxicity Induced by Zinc Oxide Nanoparticles
Author(s):
Samed Abduljabbar Ramadhan* and Ozdan Akram Ghareeb
With the growing development of nanotechnology and the increase in exposure to nanoparticles, there is an urgent need for more studies to assess the toxicity caused by these particles to the body and to find ways to avoid their harmful effects. This experiment was designed to estimate the toxicity of Zinc Oxide Nanoparticles (ZnONPs) on rats hepatic function parameters, and then noting the beneficial effect of Cichorium Intybus (CI) on those disorders that may be caused by ZnO-NPs. 24 male rats were randomly divided into 4 groups, each group comprising 6. CON group without treatment, the ZnO-NPs group received ZnO-NPs, in the ZnO-NPs+CI group animals were co-administered with a combination of ZnO-NPs with CI, and finally the animals of the CI group were dosed only with CI extract. Levels of hepatic biochemical parameters including ALT, AST and ALP were measured to detect toxic changes.. Read More»
10.54608.annalsmedical.2022.93
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