Original Article
Serum Soluble Endoglin as Predictor of Non-severe Pre-eclampsia and Severe Pre-eclampsia in early Second Trimester of Pregnancy
Author(s):
Rekha Sachan*, Vandana and Radhey Shyam
Objective: To evaluate the role of serum soluble endoglin in prediction of non-severe preeclampsia and severe preeclampsia in early second trimester (13-20 weeks) of pregnancy. Material and Methods: Prospective case–control study was carried out over a period of one and half years. Total 543 pregnant women were recruited but 43 were lost to follow up. Out of 500 pregnant women, 34 developed non severe preeclampsia (Group 2) and 16 developed severe preeclampsia (Group 3), and 51 healthy normotensive pregnant women (Group 1) were selected as controls. Serum soluble endoglin levels were measured by Human Eng (endoglin) ELISA kit. Endoglin levels were estimated by enzyme linked immune-sorbent assay technique. Results: Prevalence of hypertensive disorders of pregnancy (HDP) was 10.2%. The mean sEng levels.. Read More»
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