Research Article
Comparative Evaluation of Biocompatibility of Madhuca Longifolia Saponin Seed Extract with Sodium Hypochlorite-In Vitro Study
Author(s):
Aishuwariya T and Sindhu Ramesh*
Background: Success of a root canal therapy depends on how well a clinician eradicates the microorganisms from the complex root canal system. Synthetic irrigants have been associated with harmful side effects. Herbal products with minimal side effects are gaining importance.
Objectives: To evaluate the biocompatibility of novel irrigant from Madhuca longifolia seed extract on the L929 cell lines.
Methods: The extract was prepared by using 10 gm of the powdered sample of Madhuca longifolia with 85% methanol using Soxhlet extraction method. L929 fibroblast cell lines were purchased and cells were cultured in a humidified atmosphere at 37°C in the cell growth Dulbecco's Modified Eagle medium. Cytotoxicity test was performed using MTT assay. The median lethal concentration of the test samples were expressed as the percen.. Read More»
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