Research Article
Nasal Decongestant Effects of Vitellaria paradoxa (Shea Butter) Extracts, a Hospital Based Study
Author(s):
Opubo Benedict Lilly-Tariah, Iyeopu Miniakiri Siminialayi, Sokiprim Akoko*, Ediriverere Nosa Oghenekaro and Musa Stephen
Background: Mucosal inflammation underlies many of the specific and interrelated factors
that contribute to nasal congestion and shea butter is used by local healers as a treatment for
inflammatory conditions including nasal congestion. The aim of this study was to evaluate the
effects of extracts of Shea butter on diagnosed patients with Nasal congestion.
Methods: Forty-Two study participants were randomized into two main groups-control
(standard of care-Cetirizine, Xylometazoline) and then the shea butter/shea butter extract
group which was further subdivided into 4 groups-extract 1 (saponifiable); extract 2 (nonsaponifiable),
extract 3 (Steroid) and shea butter. Following the administration of the various
drugs, participants were followed for 24 hours with nasal washout samples taken at baseline
and 24 hours later, t.. Read More»
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