Yajie Lu

Department of Clinical Oncology, Air force medical University, Shaanxi, China

Publications

• Research Article   
  Genetically Predicted Sleep Duration in Relation to Risk of Breast Tumor
  Author(s): Litong Shao, Dan Zhao, Jing Ji and Yajie Lu*
  
  Background: Previous observational studies reported that sleep traits were associated with breast tumors. However, the causal relationship between sleep duration and breast tumors is not clear. Methods: We performed a two-sample bi-directional Mendelian Randomization (MR) analysis with publicly available Genome-Wide Association Studies (GWAS) summary statistics to detect the causal relationship between genetically predicted sleep duration and the risk of breast tumors, including breast cancer (Estrogen Receptor (ER)+/ER-, Human Epidermal Growth Factor Receptor (HER)2+/HER2-), benign breast tumors and carcinoma in situ of the breast. The Inverse Variance Weighting (IVW) method was used as the gold standard for MR results and MR Egger regression, weighted median, weighted mode and simple mode methods were taken as auxiliary analyses. .. Read More»