Research Article
An Open Label Clinical Study to Evaluate the Safety and Gastrointestinal Tolerance of ONS in Hospitalized Patients Requiring Enteral Tube Feeding
Author(s):
Chetan Mehndiratta* and Yogendra Kumar
Background: The present study aimed to investigate the compliance of the Oral Nutritional Supplement (ONS) in enteral feeding protocol on the basis of GI Tolerance and improvement in patient outcomes, including safety parameters. Design: It is a 1 month, prospective, open label, investigatorinitiated study conducted between 6 Jan 2020 to 31 January 2021. Methodology: Participants of either sex, aged ≥ 18 years, hospitalized for minimum two days, requiring enteral feeding were given two feeds of ONS (45 gm diluted in 100 mL of water) along with four standard kitchen feeds at different timings. Primary endpoint was to monitor continuous GI and stomach tolerance and effect o n G astric R esidual Volume (GRV). Secondary endpoints were change in BMI, Serum albumin levels, and adverse events monitoring. Data was analyzed descriptively using paired ttest .. Read More»
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